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On the above basis, sulforaphane has been shown to downregulate NF-κB activity in the following cell types under a variety of inflammatory conditions: bone marrow-derived dendritic cells [74]

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Acknowledgments The authors are grateful to David Lynch for the invitation to contribute this review to the research topic “Basic and Clinical Mechanisms in Friedreich Ataxia.” Conflict of interest The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest

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