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As mechanisms to dispose of both hydrogen peroxide and lipid hydroperoxides are essential to life, this indicates that in contrast to the multiple metabolic pathways that can be utilized to dispose of hydrogen peroxide, pathways for the disposal of lipid hydroperoxides are limited

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Many studies have shown that lifestyle interventions, such as physical activities and MNT, can reduce HbA1c levels by 0.3–2% and even achieve remission of diabetes, defined as an HbA1c 30% reduction in steatosis in the rosiglitazone group were both significantly greater than those in the placebo group