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This paper provides a review of the literature and a theoretical perspective on the potential roles of AA in the treatment of pain and opioid use disorder (OUD)

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The concentrations of 23 cytokines, including interleukin-3 (IL-3), interleukin-1beta (IL-1β), TNF-α, interleukin-9 (IL-9), interleukin-4 (IL-4), monocyte chemoattractant protein-1 (MCP-1), interleukin-5 (IL-5), interferon-gamma (IFN-γ), interleukin-2 (IL-2), macrophage inhibitory protein-1 alpha (MIP-1α), interleukin-13 (IL-13), interleukin-6 (IL-6), interleukin-1alpha (IL-1α), granulocyte colony-stimulating factor (G-CSF), eotaxin-CCL11 (Eotaxin), macrophage inhibitory protein-1 beta (MIP-1β), interleukin 12 p40 (IL-12P40), RANTES, interleukin-10 (IL-10), keratinocyte chemoattractant (KC), interleukin-17 (IL-17A), granulocyte macrophage-colony stimulating factor (GM-CSF) and interleukin 12 p70 (IL-12P70), were assayed in mouse colon tissue and serum samples using Luminex multiplex bead array assays with LabEx (Shanghai, China)